SAM stands for Surface to Air Missile. SAMs are fast firing, highly accurate defenses great for shooting down faster moving aircraft. SAMs are built at tech level 3 in Supreme Commander, either by an upgraded Commander, a Support Commander or T3 engineer.

There are four SAM launchers in Supreme Commander:

• UEF Anti-Air SAM Launcher: Flayer
• Cybran T3 Anti-Air SAM Launcher: Myrmidon
• Aeon T3 Anti-Air SAM Launcher: Transcender

The Forged Alliance expansion added a fourth launcher, belonging to the Seraphim faction:

• Seraphim T3 Anti-Air Defense: Iathu-ioz